Antibodies are produced by your immune system to fight infection by a virus or other organisms your system considers to be a threat. If your monospot test is negative but you have all the symptoms of mono, your doctor will likely repeat the test before doing more extensive antibody tests. Mayo Clinic: Mononucleosis Centers for Disease Control and Prevention: Epstein-Barr Virus and Infectious Mononucleosis, Combatting Modern Slavery and Human Trafficking Statement, Swollen glands in the neck and/or armpits, If symptoms and reactive lymphocytes are present but the mono test is negative, then it may be too early to detect the heterophile antibodies or the affected person may be one of a small percentage of people who do not make heterophile antibodies. Mono can affect anyone at any age, but its prevalence is highest in populations of young people, such as students in high schools or colleges, or in the military.
Diagnosis of mono is confirmed with blood testing - either a monospot test, or a full-blown blood test for EPV. Mononucleosis MedlinePlus Medical Encyclopedia [On-line information]. Vorvick, L. (2012 May 15).

utensils to yourself. The mono test detects proteins in the blood called heterophile antibodies that are produced by the immune system in response to an EBV infection. Accessed June 13, 2016.
illness when symptoms are most severe. He is an associate professor at Weill Cornell Medicine in New York City. Mononucleosis in Emergency Medicine. Mono treatment.

Cunha, B. While the Centers for Disease Control (CDC) no longer recommends the ​monospot test, many guidelines still encourage using this test to help identify the cause of mono. These could be due to mono, but could also be owed to other conditions and complications. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003454.htm.

and Clipart.com.

It is important not to rely on self-diagnosis for mono as the symptoms could be those of illnesses that need a different course of treatment. KidsHealth.org: Mononucleosis

for being selfish. This means The virus is then "dormant," or inactive. Accessed June 13, 2016. According to the Centers for Disease Control and Prevention (CDC), most people in the United States are infected by EBV at some point in their lives. Epstein-Barr Virus and Infectious Mononucleosis. Wash your hands well and often, sneeze or Mono-like symptoms can be seen in infections other than Epstein-Barr virus. transfusions, but this is much less common. Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, eds (2005). ​LabCorp's test menu provides a comprehensive list of specialty and general laboratory testing services. Epstein-Barr Virus and Infectious Mononucleosis. Mono is usually a self-limiting condition; the symptoms resolve without any specific treatment. (Oct 2015) Cunha, B. Medscape. This can help your doctor make a diagnosis if the symptoms don't go away on their own by day 10. Sometimes, your spleen or liver may enlarge and you may have to limit your activity until these organs return to normal size. Epstein-Barr virus is very common and very contagious.

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For more information, visit the Centers for Disease Control and Prevention's web page on Chronic Fatigue Syndrome. Influenza can also mimic some of the symptoms of mono but usually doesn't produce swollen neck glands. The CBC is used to determine whether the number of white blood cells (WBCs) is elevated and whether a significant number of reactive lymphocytes are present. a few weeks. Aspirin has been In pregnant women, more extensive antibody testing may be done to rule out causes other than EBV that have more potential to affect the pregnancy. Mononucleosis (mono) is a viral infection that causes a sore throat and fever. A positive monospot test accompanied by the symptoms of mono helps confirm a diagnosis of infectious mononucleosis. How Long Do Fatigue Symptoms Last in Mono? fluids. The doctor must use the patient's symptoms and other tests to distinguish between these conditions. Mayo Clinic [On-line information]. Tests: Epstein-Barr Virus (EBV) Antibody Tests; Complete Blood Count; Strep Throat Test; TORCH; CMV Tests; CSF Analysis; Blood Smear, FamilyDoctor.org: Mononucleosis Infectious Mononucleosis in Adults and Adolescents. Mononucleosis spot test. These tests may be done if the illness symptoms aren't typical for mononucleosis or you have been ill for more than four weeks. Andy Miller, MD, is board-certified in internal medicine and infectious disease. Accessed November 2012. When you start feeling better, take it slow and don't overdo it. Mono is usually caused by the Epstein-Barr virus (EBV) or similar viruses, but strep throat and some other conditions may need to be ruled out. some point while we're growing up. However, the test does have a 25% false-negative rate due to the fact that some people infected with EBV do not produce the heterophile antibodies that the mono test is designed to detect. have very mild symptoms or none at all. If a mono test is negative and suspicion it still high, then a test specific for EBV antibodies is usually performed. Available online at http://www.aafp.org/afp/20041001/1279.html. According to the Mayo Clinic, results for the monospot test, a typical blood test for mononucleosis, come back within a day. Available online at http://www.cdc.gov/ncidod/diseases/ebv.htm. A mono test is frequently ordered along with a complete blood count (CBC). Mono symptoms usually go away within 2 to 4 weeks.


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